Alzheimer’s researchers have spent years focusing on the “amyloid hypothesis” proposing that toxic ꞵ-amyloid (Aꞵ) proteins, and the plaques they form outside neurons, were the
The FDA approval of Biogen’s aducanumab, now known as Aduhelm, set a low bar that other potential antibody treatments for Alzheimer’s disease are also hopeful
The amyloid hypothesis has inspired most of Alzheimer’s research for the last 20 years. It proposes that accumulation of a protein fragment known as beta-amyloid,
The FDA’s approval of aducanumab has been shrouded by controversy, with experts quickly criticizing the FDA’s ruling, referencing two large studies showing little convincing evidence
Due to inconsistent effects of anti-amyloid therapies, such as aducanamab, a recent shift from the “amyloid hypothesis” to the “tau hypothesis”, has occurred.
This week we will be discussing the mushroom Lions Mane, or Hericium Erinaceus, and its health applications for Alzheimer’s Disease (AD). Currently,
This week we review a disease called Alzheimer-related primary progressive aphasia (PPA-AD). It is well known that a primary symptom of Alzheimer’s disease (AD) is
For quite a while, one of the most common methods of isolating disease-risk-associated genes has been a Genome Wide Association Study (GWAS) which involves genotyping
It was previously thought that fine particulate matter, produced by car exhaust and wildfires among other things, makes its way into the
A couple months ago we posted a blog about a blood test for Alzheimer’s disease (AD) that changed the game of diagnosing
This week we review the current status of a previously tested investigational treatment for Alzheimer’s disease (AD) reflecting the clinical trial
Research into the prevention and treatment of Alzheimer’s disease (AD) frequently starts small, with the discovery of risk factors that correlate with elevated deposition of
Most of our blogs emphasize treatments that directly affect the mechanisms that induce Alzheimer’s disease (AD). However, recent research into the use
Alzheimer’s disease (AD) has long eluded a cure, causing researchers to delve deeper into the biological underpinnings of the disorder for new, inventive, and multi-factorial
Most neurological disorders are associated with a biomarker, a protein or biological by-product whose concentration correlates to the development of the disorder.
Alzheimer’s disease (AD) was identified in 1901 by Alois Alzheimer but despite being known for over a century, researchers are discovering new things about the
A recent discovery of a genetically unique family has shown that developmental disorders may predispose or change the presentation of Alzheimer’s disease
Insulin is typically associated with regulating blood glucose levels and diabetes, but it also serves as a crucial signaling molecule throughout the body, including the
Memory impairment is often the hallmark symptom of Alzheimer’s disease (AD). However, research recently discovered a trend suggesting that decreased learning may preface memory loss
We frequently discuss what factors increase or reduce risk for Alzheimer’s disease (AD) and other memory-impairing disorders. However, with research constantly ongoing
Today we will discuss Hippocampal Sclerosis (HS), which causes memory impairment similar to, and frequently confused as, Alzheimer’s disease (AD). HS is often misdiagnosed
Two primary biomarkers are produced in the brains of those with Alzheimer’s disease (AD). They are misfolded versions of proteins called amyloid-β (Aβ) and tau.
Older adults and those with chronic health conditions are at higher risk of contracting Covid-19. Although social distancing precautions are very necessary to help flatten
We Have Re-Opened! We are pleased to resume clinic and research operations at Center for Cognitive Health! Please take a moment to review our plans
The newest coronavirus strain, COVID-19, has reached pandemic status. Similar to SARS (severe acute respiratory syndrome) from 2013, COVD-19 induces respiratory complications. Those 65 years
Our response to stimuli may be detrimental to our health and cognition, like being stressed while driving in traffic. Neurofeedback retrains our physiologic
The biology of how memories are made and retrieved is well studied. A new component possibly impacting our memory based upon the time
In our previous blogs we have touched upon a couple aspects of how diet can impact neurological function and risk for diseases like
Within the last few years, an interesting correlation has been discovered between the concentration of lithium in municipal water sources and the incidents of dementia
Art and music therapy are by no means new ideas, with the term art therapy first being coined in 1942 by British artist
The human genome is complex, unique to each individual, and is the primary driving force behind every biological function and dysfunction. This week’s
Many followers of this blog, and those who have participated in our clinical trials, have heard the terms beta-amyloid (Aβ) plaques and tau neurofibrillary tangles
There are, to date, few methods of non-invasive brain stimulation (NIBS) that show therapeutic potential for neurological dysfunction. The most commonly used forms
Many facets of our lives are profoundly impacted by our underlying genetic makeup from birth. One particularly impactful genetic difference involves the X
As we all know, sleep plays a critical role in brain functioning. One such function is memory, with sleep enhancing memory
As we look back upon the events of the last decade, it seems fitting to also review thevarious types of memory,
Known since 1992, the French diet is high in saturated fats, a risk for coronary heart disease (CHD), yet they have less than half the
We recently introduced the gut-brain axis as a bidirectional communication loop. Our bodies control, yet are in part controlled, by the living microorganisms within our
As we discussed last week, our microbiome has profound impacts outside of the digestive system including the central nervous system (CNS). The
We each have a unique and complex network of microbes living within our guts known as a microbiome. It is comprised
Aging can be hard to embrace, but it can also be a time to try new things and explore interests that time may not have
It is normal for our brains to shrink as we age but abnormal to lose basic cognitive function or brain cells in large numbers. Alzheimer’s
A 17-acre elderly care village named Landais Alzheimer is currently being built near the city of Dax nestled in southwestern France. It may appear to
We have all been told how important it is for our health to lead an active lifestyle. Physical activity has many positive health benefits, but
Why do people get Alzheimer’s disease (AD)? The cause of this disease is still widely unknown, but after many years of studying AD caloric intake,
The Alzheimer’s Foundation of America (AFA) have added a new tool to their website in the form of an Online Screening Test that can help
Turmeric is a commonly used natural spice in South Asian cuisine such as curry. It is a common question whether or not turmeric and curcumin
With so many advertisements claiming that certain medications treat Alzheimer’s disease, how can we tell which one’s are legitimate? There are 4 FDA approved medications
Our Stories, by the Alzheimer’s Association, features the unique stories of 5 individuals with Alzheimer’s disease. These interactive stories help to notice changes in yourself
A recent article published on ALZFORUM discussed research from the first longitudinal study that conducted repeated scans on older adults for both amyloid and tau
Does Alzheimer’s disease pathology accumulate in our brains in our younger years without making us symptomatic? Typically, individuals don’t get evaluated for Alzheimer’s disease (AD)
Each year the Alzheimer’s Foundation of America awards a $25,000 grant to a nonprofit organization to help fund new programs or services within the community.
The Alzheimer’s Foundation of America is an organization that provides support and education to those living with Alzheimer’s disease, as well as, their caregivers and
How can we tell the difference between normal age related memory symptoms and early Alzheimer’s disease symptoms? It is important to note that not everyone
Sleep problems and disorders are relatively common among seniors. Many individuals with a neurodegenerative disease complain of experiencing insomnia, excessive daytime sleepiness, or abnormal motor
We have been taught the importance of brushing our teeth since childhood, but could maintaining healthy oral hygiene protect us from getting Alzheimer’s disease? The
Clinical trials tend to have a cloud of negative talk hovering over them. Participating in something that involves your health can be daunting and scary,
According to the Alzheimer’s Association, 16.1 million Americans provide unpaid care for people with Alzheimer’s disease or other dementias, resulting in an estimated 18.4 billion
The Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study was a 12 month, observational, open-label, longitudinal study done from February 2016 to December 2017. This study
Many of us are stretched for time and lead busy lifestyles. By the time we reach the end of our day, the idea of sitting
Acti-v8 Your Brain is a program that is designed to help individuals sustain a healthy brain! All of the information that each of the 8
Researchers are looking into a new theory that may lead to a different approach in the treatment of Alzheimer’s disease. Recently on our Facebook page we
For many ailments and conditions, over-the-counter products are readily available to help consumers find relief or treat various medical symptoms. When it comes to the
Michael Mega, MD, PhD Director, Center for Cognitive Health The definition of Alzheimer’s disease is changing. With the ability to visualize
Michael Mega, MD, PhD Director, Center for Cognitive Health Do you have a family history of Alzheimer’s disease? If you do there is much you
In the quest to conquer Alzheimer’s disease, new drugs that can be used long before the effects of the disease take hold are being tested.
On top of providing top notch care to patients with memory impairment and cognitive decline, we are committed to increasing awareness of Alzheimer’s disease causes,